Search results for "methods [DNA Mutational Analysis]"
showing 10 items of 245 documents
A method for genome-wide analysis of DNA helical tension by means of psoralen-DNA photobinding
2010
The helical tension of chromosomal DNA is one of the epigenetic landmarks most difficult to examine experimentally. The occurrence of DNA crosslinks mediated by psoralen photobinding (PB) stands as the only suitable probe for assessing this problem. PB is affected by chromatin structure when is done to saturation; but it is mainly determined by DNA helical tension when it is done to very low hit conditions. Hence, we developed a method for genome-wide analysis of DNA helical tension based on PB. We adjusted in vitro PB conditions that discern DNA helical tension and applied them to Saccharomyces cerevisiae cells. We selected the in vivo cross-linked DNA sequences and identified them on DNA …
La intervenció de la/treballador/a social sanitari a la Comunitat Valenciana
2012
The purpose of this document is to provide both, professionals and citizens, with information about the procedures and processes of intervention developed by social workers within the different health institutions of the Community of Valencia. It is important to identify the specificity of Social Work in the Health Care System in order to consolidate Professional Identity from the homogeneity in the processes and procedures of intervention and the identification of the duties carried out by these professionals in the different health institutions/services of the Community of Valencia.
Zināšanu vadīšanas metožu pilnveidošana organizācijās
2013
Elektroniskā versija nesatur pielikumus
Complex adaptative systems and computational simulation in Archaeology
2017
Traditionally the concept of ‘complexity’ is used as a synonym for ‘complex society’, i.e., human groups with characteristics such as urbanism, inequalities, and hierarchy. The introduction of Nonlinear Systems and Complex Adaptive Systems to the discipline of archaeology has nuanced this concept. This theoretical turn has led to the rise of modelling as a method of analysis of historical processes. This work has a twofold objective: to present the theoretical current characterized by generative thinking in archaeology and to present a concrete application of agent-based modelling to an archaeological problem: the dispersal of the first ceramic production in the western Mediterranean.
Optimal passive-damping design using a decentralized velocity-feedback H-infinity approach
2012
In this work, a new strategy to design passive energy dissipation systems for vibration control of large structures is presented. The method is based on the equivalence between passive damping systems and fully decentralized static velocity-feedback controllers. This equivalence allows to take advantage of recent developments in static output-feedback control design to formulate the passive-damping design as a single optimization problem with Linear Matrix Inequality constraints. To illustrate the application of the proposed methodology, a passive damping system is designed for the seismic protection of a five-story building with excellent results. Peer Reviewed
Science case study and scientific simulations for the enhanced X-ray Timing Polarimetry mission, eXTP
2022
The X-ray astronomy mission eXTP (enhanced X-ray Timing Polarimetry) is designed to study matter under extreme conditions of density, gravity and magnetism. Primary goals are the determination of the equation of state (EoS) of matter at supranuclear density, the physics in extremely strong magnetic fields, the study of accretion in strong-field gravity (SFG) regime. Primary targets include isolated and binary neutron stars, strong magneticfield systems like magnetars, and stellar-mass and supermassive black holes. In this paper we report about key observations and simulations with eXTP on the primary objectives involving accretion under SFG regimes and determination of NS-EoS.
Computational approach to compact Riemann surfaces
2017
International audience; A purely numerical approach to compact Riemann surfaces starting from plane algebraic curves is presented. The critical points of the algebraic curve are computed via a two-dimensional Newton iteration. The starting values for this iteration are obtained from the resultants with respect to both coordinates of the algebraic curve and a suitable pairing of their zeros. A set of generators of the fundamental group for the complement of these critical points in the complex plane is constructed from circles around these points and connecting lines obtained from a minimal spanning tree. The monodromies are computed by solving the defining equation of the algebraic curve on…
Visualizing linguistic variation in a network of Latin documents and scribes
2018
This article explores whether and how network visualization can benefit philological and historical-linguistic study. This is illustrated with a corpus-based investigation of scribes' language use in a lemmatized and morphologically annotated corpus of documentary Latin (Late Latin Charter Treebank, LLCT2). We extract four continuous linguistic variables from LLCT2 and utilize a gradient colour palette in Gephi to visualize the variable values as node attributes in a trimodal network which consists of the documents, writers, and writing locations underlying the same corpus. We call this network the "LLCT2 network". The geographical coordinates of the location nodes form an approximate map, …
Territoires urbains en transition. Monographie d’un quartier populaire en résilience écologique, Editions Universitaires de Dijon, décembre 2015
2015
National audience; Que faites-vous pour la planète? Vous prenez le vélo pour aller travailler? Vous recyclez des tissus pour fabriquer et peut-être vendre des vêtements? Vous avez choisi une pratique sportive durable dans un club près de chez vous? Vous mangez bio? Vous utilisez les réseaux sociaux pour faire connaître vos éco-gestes à vos voisins ou à l'autre bout du monde? Imaginez... A quoi pourrait ressembler un quartier populaire en 2050, si on ne fait rien pour protéger l’environnement ou, à l'inverse, si on fait tout pour le préserver?Une équipe pluridisciplinaire a enquêté durant deux ans, entre 2012 et 2014, auprès de la population d'un de ces quartiers, la Fontaine d'Ouche, en pro…